Rui-an WANG M.D., Ph.D. Mentor for the doctorate postgraduate; Professor and Chairman of Department of Pathology of the Fourth Military Medical University; Associate Director General of Shaanxi Provincial Anti-cancer Association of Chinese Anti-Cancer Association. His publications are over 40, including in the international high ranking journals like Nature, Nature Cell Biology, EMBO Journal, Journal of Cell Biology, and Oncogene. His representative publications include:
1 Wang RA, Nakane PK, Koji T. Autonomous cell death of mouse male germ cells during fetal and postnatal period. Biology of Reproduction 1998, 58(5):1250-1256.
2 Wang RA, Zhao GQ. Transforming growth factor beta signal transducer Smad2 is expressed in mouse meiotic germ cells, Sertoli cells, and Leydig cells during spermatogenesis. Biology of Reproduction. 1999 Oct;61(4):999-1004.
3 Mazumdar A, Wang RA (Co-first author), Mishra KM, Adam L, Yarmand RB, Mandal M, Vadlamudi RK, Kumar R. Transcriptional repression of estrogen by metastasis-associated protein I corepressor. Nature Cell Biology, 2001, 3, 30-37.
4 Kumar R, Wang RA, Mazumdar A, Talukder AH, Adam L, Bagheri-Yarmand R, Sahin A, and Kumar R. Identification of a naturally occurring variant of metastasis associated protein-1 that sequesters estrogen receptor and upregulated in estrogen receptor-negative human breast tumors. Nature, 2002, Aug 8, 418: 654-657.
5 Wang RA and Kumar R. The discovery and function of MTA1s in ER cytoplasmic sequestration. In CS Watson edited “The Identities of Membrane Steroid Receptors (Boston: Kluwer Academic Publishers), pp. 119–124.
6 Wang RA, Mazumdar A, Vadlamudi RK, Kumar R. P21-activated kinase phosphorylates and transactivates estrogen receptor and promotes hyperplasia in mammary epithelium. EMBO Journal 2002, Oct 15, 21(20): 5437-5447.
7 Wang RA, Vadlamudi RK, Beuvink I, Hynes NE, Kumar R. Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glands. Journal of Cell Biology. 2003 May 12;161(3):583-92.
8 Wang RA, Zhao M, Meistrich ML, Kumar R. Stage-specific Expression of Dynein Light Chain-1 and Its Interacting Kinase, p21-activated Kinase-1, in Rodent Testes: Implications in Spermiogenesis. J. Histochem. Cytochem. 2005 Oct, 53(10):1235-1243.
9 Wang RA, Zhang H, Balasenthil S, Medina D, Kumar R. PAK1 hyperactivation is sufficient for mammary gland tumor formation. Oncogene 2006, 25:2931-2936.